Description

2'-Methyl-16,17-Cyclohexaneprogesterone is a high-purity synthetic steroid derivative, a modified progesterone analog designed for advanced research and development. This compound is critical for pharmaceutical and life science applications where precise molecular structure and high chemical integrity are paramount. It serves as a key intermediate or reference standard for researchers in steroid chemistry, hormone receptor studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel steroid-based pharmaceuticals and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating progesterone receptor binding, selectivity, and downstream signaling pathways.
• Hormone Analog Development: Acts as a structural template for the research and development of new hormone analogs with modified biological activity and metabolic stability.
• Academic & Institutional Research: Employed in university and institutional laboratories for fundamental research in organic synthesis, medicinal chemistry, and endocrinology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-specific projects.
• Analytical Standard: Utilized as a high-purity standard for method development and validation in analytical techniques like HPLC and LC-MS for steroid analysis.

Basic Information

Product Name	2'-Methyl-16,17-Cyclohexaneprogesterone
CAS No.	116169-22-3
Molecular Formula	C24H36O2
Molecular Weight	356.55 g/mol
Synonyms	2'-Methyl-16,17-cyclohexanoprogesterone; 16,17-Cyclohexanoprogesterone, 2'-methyl-; (8S,9S,10R,13S,14S,17R)-17-acetyl-2',10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-16-ol; Progesterone derivative with 2'-methyl and 16,17-cyclohexano modification
EINECS	Contact for details

Quality Control

Our 2'-Methyl-16,17-Cyclohexaneprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.