Description

18-Ethynylprogesterone is a synthetic steroid derivative of progesterone, featuring an ethynyl group at the C18 position. This structural modification is of significant interest in pharmaceutical research for developing novel hormone-based therapeutics and exploring advanced synthetic pathways. It serves as a critical pharmaceutical intermediate and a valuable reference standard for analytical and research purposes. Key industries that utilize this compound include pharmaceutical R&D, academic research institutions, and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard and probe in studies of progesterone receptor activity and steroidogenesis.
• Academic & Industrial R&D: Employed in method development and as a starting material for creating new chemical entities in medicinal chemistry.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method validation in laboratories.

Basic Information

Product Name	18-Ethynylprogesterone
CAS No.	115940-37-9
Molecular Formula	C22H30O2
Molecular Weight	326.48 g/mol
Synonyms	18-Ethynyl-4-pregnene-3,20-dione; 18-Ethynylpregn-4-ene-3,20-dione; 18-Ethynyl-progesterone; 18-Ethynyl P4; 18-Ethynyl-PRG; Pregna-4-ene-3,20-dione, 18-ethynyl-
EINECS	Contact for details

Quality Control

Our 18-Ethynylprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.