Description

Phenol, 4-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-[4-(1-Methylethyl)Phenyl]-1-Butenyl]-, Dihydrogen Phosphate (Ester) is a high-purity, complex organic phosphate ester of significant interest in advanced pharmaceutical research and development. This compound matters as a critical synthetic intermediate or potential active pharmaceutical ingredient (API) precursor, enabling the creation of novel therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing new drugs, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Biochemical Research: Used in life science research to study enzyme interactions, signal transduction pathways, and cellular mechanisms.
• API Development: Acts as a precursor in the development of potential Active Pharmaceutical Ingredients (APIs) with specific receptor activity.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and safety profiles of new chemical entities.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Studies: Supplied for use in pharmacological and toxicological evaluations during early-stage drug discovery.

Basic Information

Item	Details
Product Name	Phenol, 4-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-[4-(1-Methylethyl)Phenyl]-1-Butenyl]-, Dihydrogen Phosphate (Ester)
CAS No.	115767-64-1
Molecular Formula	C29H36NO5P
Molecular Weight	509.58 g/mol
Synonyms	Tamoxifen Phosphate Ester; (Z)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-(4-isopropylphenyl)-1-butenyl]phenyl Dihydrogen Phosphate; Tamoxifen Dihydrogen Phosphate; 4-[(Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-(4-propan-2-ylphenyl)but-1-en-1-yl]phenyl Dihydrogen Phosphate; Endoxifen Phosphate; Afimoxifene Phosphate; TAM Phosphate
EINECS	Contact for details

Quality Control

Our Phenol, 4-[1-[4-[2-(Dimethylamino)Ethoxy]Phenyl]-2-[4-(1-Methylethyl)Phenyl]-1-Butenyl]-, Dihydrogen Phosphate (Ester) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.