Description

6-Methoxy-3,4-Dihydronaphthalen-1-Yl Trifluoromethanesulfonate is a high-value triflate ester intermediate, prized for its reactivity as a versatile electrophile in cross-coupling reactions. This compound is essential for constructing complex molecular architectures, particularly in the synthesis of advanced pharmaceutical ingredients and organic electronic materials. It is a critical building block for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides with specific activity profiles.
• Material Science Precursor: Serves as a monomer or intermediate in the production of organic semiconductors and light-emitting materials for OLED applications.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Negishi, and Stille couplings to form carbon-carbon bonds.
• Organic Synthesis Research: A versatile electrophile in academic and industrial R&D for constructing complex, polycyclic aromatic and heteroaromatic systems.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Methoxy-3,4-Dihydronaphthalen-1-Yl Trifluoromethanesulfonate
CAS No.	115375-59-2
Molecular Formula	C₁₃H₁₃F₃O₄S
Molecular Weight	322.30 g/mol
Synonyms	1,2,3,4-Tetrahydro-6-methoxy-1-naphthalenyl trifluoromethanesulfonate; 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-yl triflate; 6-Methoxy-1-tetralol triflate; 6-Methoxy-α-tetralol trifluoromethanesulfonate; 1-Triflyloxy-6-methoxy-1,2,3,4-tetrahydronaphthalene; 6-Methoxy-1,2,3,4-tetrahydronaphthalen-1-yl trifluoromethanesulfonate; 6-Methoxy-1-tetralyl triflate
EINECS	Contact for details

Quality Control

Our 6-Methoxy-3,4-Dihydronaphthalen-1-Yl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.