Description

Trimethyl(Bromodifluoromethyl)Silane is a versatile organosilicon reagent featuring a reactive bromodifluoromethyl group. This compound is a valuable building block in synthetic organic chemistry, enabling the efficient introduction of the difluoromethyl moiety into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of difluoromethylated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the difluoromethyl group can improve biological activity and metabolic stability.
• Material Science: Building block for modifying surfaces or creating specialty polymers and silicones with unique fluorinated properties.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and cross-coupling reactions to install the -CF2Br group.
• Fluorine Chemistry Research: Essential tool in academic and industrial R&D labs exploring new fluorination methodologies and organofluorine compounds.

Basic Information

Product Name	Trimethyl(Bromodifluoromethyl)Silane
CAS No.	115262-01-6
Molecular Formula	C4H9BrF2Si
Molecular Weight	203.10 g/mol
Synonyms	Bromodifluoromethyltrimethylsilane; (Bromodifluoromethyl)trimethylsilane; Trimethyl(bromodifluoromethyl)silicon; TMS-CF2Br; Silane, bromodifluoromethyltrimethyl-; (Bromodifluoromethyl)trimethylsilane; Trimethylsilyl bromodifluoromethane
EINECS	Contact for details

Quality Control

Our Trimethyl(Bromodifluoromethyl)Silane is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.