Description

(Chlorodifluoromethyl)Trimethylsilane is a versatile organosilicon reagent featuring a reactive chlorodifluoromethyl group. This compound is valued for its role as a key synthetic intermediate in the preparation of fluorinated organic molecules, enabling the introduction of the CF2 moiety. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Serves as a building block for creating novel fluorinated pesticides and herbicides.
• Fluorinated Material Precursor: Employed in the research and development of specialty fluoropolymers and surface-modifying agents.
• Organic Synthesis Reagent: Acts as a source of the :CF2 carbene or a nucleophilic difluoromethylating agent under specific conditions.
• Liquid Crystal & OLED Material Research: Utilized in the creation of fluorinated components for electronic display and lighting applications.
• Cross-Coupling Reactions: Participates in palladium-catalyzed reactions to form carbon-carbon bonds with fluorinated groups.

Basic Information

Product Name	(Chlorodifluoromethyl)Trimethylsilane
CAS No.	115262-00-5
Molecular Formula	C4H9ClF2Si
Molecular Weight	158.65 g/mol
Synonyms	Trimethyl(chlorodifluoromethyl)silane; Chlorodifluoromethyltrimethylsilane; (Chlorodifluoromethyl)trimethylsilicon; TMSCF2Cl; Ruppert-Prakash Reagent (modified); Difluorochloromethyltrimethylsilane; Silane, trimethyl(chlorodifluoromethyl)-; (Trimethylsilyl)difluorochloromethane
EINECS	Contact for details

Quality Control

Our (Chlorodifluoromethyl)Trimethylsilane is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and away from heat, sparks, and open flame. Keep under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.