Description

3-Aminooxy-n-Propyl (Dimethyl-T-Butylsilyl) Ether is a specialized organosilicon compound featuring a protected aminooxy functional group. This chemical is a valuable synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for the selective modification of carbonyl compounds. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and complex organic materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), especially for creating oxime-based prodrugs or conjugates.
• Bioconjugation Reagent: Facilitates the site-specific labeling and cross-linking of biomolecules (proteins, antibodies) via reaction with aldehydes and ketones.
• Polymer Modification: Serves as a functional monomer or grafting agent to introduce aminooxy groups into polymer backbones for advanced material properties.
• Carbohydrate Chemistry: Employed in the protection and selective derivatization of sugar molecules and glycoconjugates.
• Solid-Phase Synthesis: Acts as a linker or building block on resin supports for the combinatorial synthesis of compound libraries.
• Analytical Chemistry: Used as a derivatization agent for the detection and analysis of carbonyl-containing compounds via chromatography or spectrometry.

Basic Information

Product Name	3-Aminooxy-n-Propyl (Dimethyl-T-Butylsilyl) Ether
CAS No.	114778-46-0
Molecular Formula	C9H23NO2Si
Molecular Weight	205.37 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]propylamine N-oxide; O-[3-[(tert-Butyldimethylsilyl)oxy]propyl]hydroxylamine; 3-(N-tert-Butyldimethylsilyloxyamino)propyl ether; TBDMS-protected 3-aminooxypropyl ether; 3-Aminopropoxy-tert-butyldimethylsilane; Aminooxypropyl TBDMS ether; N-(3-((tert-Butyldimethylsilyl)oxy)propyl)hydroxylamine
EINECS	Contact for details

Quality Control

Our 3-Aminooxy-n-Propyl (Dimethyl-T-Butylsilyl) Ether is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance as a critical synthetic reagent. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.