Description

Methyl Cbz-Amino(Diethoxyphosphoryl)Acetate is a specialized organophosphorus building block of significant interest in advanced synthetic chemistry. Its core value lies in its bifunctional structure, incorporating both a protected amino group and a phosphonate moiety, which makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly in the synthesis of peptide mimetics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting protease enzymes.
• Peptidomimetic Synthesis: Used to incorporate non-hydrolyzable phosphonate isosteres into peptide backbones, enhancing metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and plant growth regulators with phosphonate activity.
• Chemical Biology Probes: Employed in the creation of activity-based probes and inhibitors for studying phosphonate-dependent biological pathways.
• Ligand Development: Useful for synthesizing complex chelating agents and organocatalysts for asymmetric synthesis.
• Material Science: Potential monomer or additive in the development of specialty polymers with unique properties.

Basic Information

Product Name	Methyl Cbz-Amino(Diethoxyphosphoryl)Acetate
CAS No.	114684-69-4
Molecular Formula	C₁₅H₂₂NO₇P
Molecular Weight	359.31 g/mol
Synonyms	Methyl N-[(benzyloxy)carbonyl]amino(diethoxyphosphoryl)acetate; (Benzyloxycarbonylamino)(diethoxyphosphoryl)acetic acid methyl ester; Cbz-NH-CH(PO(OEt)₂)-COOCH₃; Z-Amino(diethoxyphosphoryl)acetic acid methyl ester; N-Carbobenzoxyamino(diethoxyphosphoryl)acetic acid methyl ester; Methyl (N-carbobenzyloxyamino)(diethoxyphosphoryl)acetate; Phosphonoglycine derivative; A phosphonate analog of a protected amino acid ester.
EINECS	Contact for details

Quality Control

Every batch of Methyl Cbz-Amino(Diethoxyphosphoryl)Acetate is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.