Description

(2R)-2-Bromo-Butanoic Acid Methyl Ester is a high-purity chiral building block essential for stereoselective synthesis. This compound matters as a versatile intermediate for introducing the (2R)-2-bromo-butanoyl moiety into complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry is critical for biological activity.
• Asymmetric Synthesis: Serves as an electrophilic reagent in stereocontrolled carbon-carbon bond-forming reactions, such as alkylations and Reformatsky-type reactions.
• Ligand and Catalyst Development: A precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable tool in organic chemistry research for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	(2R)-2-Bromo-Butanoic Acid Methyl Ester
CAS No.	114438-75-4
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	Methyl (2R)-2-Bromobutanoate; (R)-Methyl 2-Bromobutanoate; (R)-2-Bromobutyric Acid Methyl Ester; Methyl (R)-(-)-2-Bromobutanoate; (R)-(-)-Methyl 2-Bromobutanoate; (2R)-2-Bromobutanoic Acid Methyl Ester; (R)-2-Bromobutanoic Acid Methyl Ester; Methyl (R)-2-Bromobutanoate
EINECS	Contact for details

Quality Control

Our (2R)-2-Bromo-Butanoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.