Description

4-[(2E)-3-(Dimethylamino)-1-Oxo-2-Propen-1-Yl]Benzoic Acid Methyl Ester is a specialized organic intermediate featuring a conjugated enone system with a dimethylamino substituent. This molecular architecture makes it a valuable synthon for constructing complex heterocyclic and pharmaceutical scaffolds. It is primarily sought by research and development chemists in the fine chemical and pharmaceutical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those with chalcone or related frameworks.
• Organic Synthesis Reagent: Used in Michael addition reactions, cyclization processes, and as a precursor for more complex molecules in academic and industrial R&D.
• Agrochemical Research: Intermediate in the development of novel active ingredients for crop protection products.
• Material Science: Potential monomer or precursor for functional polymers and advanced organic materials.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized chromophores due to its extended conjugation.

Basic Information

Product Name	4-[(2E)-3-(Dimethylamino)-1-Oxo-2-Propen-1-Yl]Benzoic Acid Methyl Ester
CAS No.	114431-72-0
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	Methyl 4-[(1E)-3-(dimethylamino)-1-oxo-2-propen-1-yl]benzoate; Methyl 4-[(E)-3-(dimethylamino)acryloyl]benzoate; (E)-Methyl 4-(3-(dimethylamino)acryloyl)benzoate; 4-(3-(Dimethylamino)acryloyl)benzoic acid methyl ester; 114431-72-0; Benzoic acid, 4-[(1E)-3-(dimethylamino)-1-oxo-2-propen-1-yl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-[(2E)-3-(Dimethylamino)-1-Oxo-2-Propen-1-Yl]Benzoic Acid Methyl Ester adheres to stringent in-process controls and final batch testing to ensure consistent purity and identity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, related substances, and physical characteristics. We support cGMP compliance for pharmaceutical applications and can tailor quality specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.