Description

tert-Butylmethylsilyl Glycidyl Ether is a specialized organosilicon compound featuring a reactive epoxide (glycidyl) group protected by a tert-butyldimethylsilyl moiety. This unique structure makes it a valuable versatile building block and protective group reagent in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in nucleoside and carbohydrate chemistry.
• Protective Group Chemistry: Used to introduce the acid-labile tert-butyldimethylsilyl (TBDMS) protecting group for alcohols and other functional groups under mild conditions.
• Polymer Modification: Serves as a functional monomer or cross-linking agent in the production of specialty silicones and epoxy-based polymers.
• Agrochemical Synthesis: Intermediate in the creation of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in surface functionalization and the development of advanced hybrid organic-inorganic materials.
• Liquid Crystal & OLED Precursor: Employed in the synthesis of intermediates for electronic display and lighting materials.

Basic Information

Item	Details
Product Name	tert-Butylmethylsilyl Glycidyl Ether
CAS No.	114413-26-2
Molecular Formula	C10H22O2Si
Molecular Weight	202.37 g/mol
Synonyms	Glycidyl tert-Butyldimethylsilyl Ether; [(2,2-Dimethylpropyl)dimethylsilyl]methyloxirane; TBDMS Glycidyl Ether; tert-Butyldimethylsilyl Glycidyl Ether; (Oxiran-2-ylmethoxy)(tert-butyl)dimethylsilane; 2-[(tert-Butyldimethylsilyloxy)methyl]oxirane; (tert-Butyldimethylsilyl)methyl Glycidyl Ether; Glycidyloxy-tert-butyldimethylsilane
EINECS	Contact for details

Quality Control

Our tert-Butylmethylsilyl Glycidyl Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.