Description

Citric Acid tert-Butyl Ester is a specialized organic ester derived from citric acid, serving as a versatile building block and intermediate in advanced chemical synthesis. Its value lies in its ability to introduce tert-butyl protecting groups, which are crucial for controlling reactivity and stability in sensitive manufacturing processes. This high-purity intermediate is essential for industries such as pharmaceuticals, agrochemicals, and fine chemicals, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing acid-labile protecting groups.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where controlled release and stability are critical.
• Polymer Modification: Acts as a monomer or cross-linking agent in the creation of specialty polymers with tailored properties.
• Fine Chemical Production: Employed in multi-step organic synthesis for fragrances, flavors, and other high-value chemical products.
• Bioconjugation Chemistry: Useful in the development of prodrugs and bioconjugates due to its cleavable ester linkage under specific conditions.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways.

Basic Information

Product Name	Citric Acid tert-Butyl Ester
CAS No.	114340-52-2
Molecular Formula	C15H24O7
Molecular Weight	316.35 g/mol
Synonyms	1,2,3-Propanetricarboxylic acid, 2-hydroxy-, 1,3,5-tris(1,1-dimethylethyl) ester; Tris(tert-butyl) citrate; tert-Butyl citrate; Citric acid tris(tert-butyl) ester; 2-Hydroxy-1,2,3-propanetricarboxylic acid tris(tert-butyl) ester; Tris-tert-butyl citrate; Citric Acid tert-Butyl Ester (triester)
EINECS	Contact for details

Quality Control

Our Citric Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The product may be hygroscopic (moisture-sensitive); ensure containers are sealed after use to prevent moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.