Description

(E)-3-(3,4-Dimethoxyphenyl)-1-(6-Hydroxy-2,3,4-Trimethoxyphenyl)Prop-2-En-1-One is a high-purity synthetic chalcone derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a versatile pharmaceutical intermediate and a critical building block in organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Chemical Synthesis Building Block: Utilized in organic synthesis for constructing complex polycyclic structures and heterocycles due to its reactive α,β-unsaturated ketone moiety.
• Biochemical Research: Employed as a reference standard or probe compound in enzymatic assays and biological screening libraries.
• Material Science Precursor: Investigated for the development of organic semiconductors, nonlinear optical materials, and advanced polymers.

Basic Information

Product Name	(E)-3-(3,4-Dimethoxyphenyl)-1-(6-Hydroxy-2,3,4-Trimethoxyphenyl)Prop-2-En-1-One
CAS No.	114021-62-4
Molecular Formula	C20H22O7
Molecular Weight	374.39 g/mol
Synonyms	1-(6-Hydroxy-2,3,4-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-2-propen-1-one; (E)-1-(6-Hydroxy-2,3,4-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one; 2-Propen-1-one, 1-(6-hydroxy-2,3,4-trimethoxyphenyl)-3-(3,4-dimethoxyphenyl)-, (E)-; Chalcone derivative; Hydroxytrimethoxychalcone; Polyhydroxylated chalcone; NSC 407296
EINECS	Contact for details

Quality Control

Our (E)-3-(3,4-Dimethoxyphenyl)-1-(6-Hydroxy-2,3,4-Trimethoxyphenyl)Prop-2-En-1-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.