Description

2'-Hydroxy-3,4,4',6'-Tetramethoxychalcone is a specialized, high-purity chalcone derivative with significant potential in advanced research and development. This compound matters as a key synthetic intermediate and a promising scaffold for developing novel bioactive molecules, particularly in pharmaceutical discovery. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery, material science, and as a reference standard.

Application

• Pharmaceutical Research & Development: Serves as a critical synthetic intermediate and a core scaffold for the design and synthesis of new drug candidates, particularly in anti-inflammatory and anticancer research.
• Biochemical Research: Used as a reference standard and a tool compound in enzymatic and cellular assays to study biological pathways and mechanisms of action.
• Agrochemical Development: Acts as a precursor for developing novel plant growth regulators or crop protection agents due to its bioactive chalcone structure.
• Fine Chemical Synthesis: Employed as a versatile building block in the synthesis of complex natural product analogs and other high-value specialty chemicals.
• Material Science: Investigated for its potential application in the development of organic semiconductors or advanced polymeric materials due to its conjugated molecular framework.
• Cosmeceutical Research: Explored for potential use in skincare formulations, leveraging the antioxidant properties common to many polyphenolic chalcone derivatives.

Basic Information

Product Name	2'-Hydroxy-3,4,4',6'-Tetramethoxychalcone
CAS No.	114021-60-2
Molecular Formula	C19H20O6
Molecular Weight	344.36 g/mol
Synonyms	2'-Hydroxy-3,4,4',6'-tetramethoxychalcone; 1-(2-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one; 3,4,4',6'-Tetramethoxy-2'-hydroxychalcone; Chalcone, 2'-hydroxy-3,4,4',6'-tetramethoxy-; (E)-1-(2-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one; 2'-Hydroxy-3,4,4',6'-tetramethoxy-trans-chalcone; NSC 407303
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We provide material that meets high-purity specifications, typically ≥95% to ≥98% by HPLC analysis, suitable for advanced synthetic and screening applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere to minimize potential oxidation. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.