Description

(3β)-3-(tert-Butyldimethylsilyl)Oxy-Chol-5-En-24-Oic Acid Methyl Ester is a high-purity, protected steroid derivative that serves as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile and reactive scaffold for the targeted construction of complex steroidal molecules, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly those developing novel therapeutic agents, reference standards, and specialized biochemical tools.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating steroidal analogs for biological testing.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Synthesis: Employed in the preparation of labeled steroids (e.g., deuterated, C13) for metabolic studies and tracer analysis.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value steroidal compounds for specialized applications.

Basic Information

Product Name	(3β)-3-(tert-Butyldimethylsilyl)Oxy-Chol-5-En-24-Oic Acid Methyl Ester
CAS No.	114011-35-7
Molecular Formula	C32H56O3Si
Molecular Weight	516.87 g/mol
Synonyms	Methyl 3β-[(tert-butyldimethylsilyl)oxy]chol-5-en-24-oate; 3β-(tert-Butyldimethylsiloxy)cholest-5-en-24-oic Acid Methyl Ester; 3β-TBDMS-Cholesten-24-oic Acid Methyl Ester; (3β)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]chol-5-en-24-oic Acid Methyl Ester; Methyl 3β-(t-butyldimethylsilyloxy)-5-cholen-24-oate; TBDMS-Protected Methyl Cholenate; Steroid TBDMS Ether Methyl Ester Intermediate
EINECS	Contact for details

Quality Control

Our (3β)-3-(tert-Butyldimethylsilyl)Oxy-Chol-5-En-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.