Description

2-Fluoro-3-Iodopyridine is a high-value halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogenated pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags used in biochemical and diagnostic applications.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Sonogashira couplings to form biaryl systems.

Basic Information

Product Name	2-Fluoro-3-Iodopyridine
CAS No.	113975-22-7
Molecular Formula	C5H3F I N
Molecular Weight	222.99 g/mol
Synonyms	3-Iodo-2-fluoropyridine; 2-Fluoro-3-iodopyridine; Pyridine, 2-fluoro-3-iodo-; 3-Iodo-2-fluoro-pyridine; 2-Fluoropyridine-3-iodide; 2-F-3-I-Pyridine; 2-Fluoro-3-iodo-pyridine; 113975-22-7
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodopyridine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures material integrity for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent photodegradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.