Description

[(5-Methyl-1H-Pyrrol-2-Yl)Methyl]Phosphonic Acid Diethyl Ester is a specialized organophosphorus compound featuring a pyrrole moiety, serving as a versatile key synthetic intermediate and ligand precursor in advanced chemical synthesis. Its unique structure makes it valuable for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research institutions and industrial manufacturers engaged in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Ligand for Catalysis: Serves as a precursor for phosphine-based ligands used in transition metal catalysis, enabling efficient cross-coupling and hydrogenation reactions.
• Material Science Research: Employed in the development of functional organic materials, including metal-organic frameworks (MOFs) and polymers with specific electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.
• Organic Synthesis: Acts as a phosphorylating agent or a protected phosphonate group in multi-step synthetic routes for complex natural products and fine chemicals.

Basic Information

Product Name	[(5-Methyl-1H-Pyrrol-2-Yl)Methyl]Phosphonic Acid Diethyl Ester
CAS No.	113848-06-9
Molecular Formula	C10H18NO3P
Molecular Weight	231.23 g/mol
Synonyms	Diethyl [(5-Methyl-1H-pyrrol-2-yl)methyl]phosphonate; Diethyl (5-Methyl-1H-pyrrol-2-ylmethyl)phosphonate; Phosphonic acid, P-[(5-methyl-1H-pyrrol-2-yl)methyl]-, diethyl ester; (5-Methyl-1H-pyrrol-2-ylmethyl)phosphonic acid diethyl ester; Diethyl (5-methyl-1H-pyrrol-2-ylmethyl)phosphonate; Diethyl ((5-methyl-1H-pyrrol-2-yl)methyl)phosphonate
EINECS	Contact for details

Quality Control

Our [(5-Methyl-1H-Pyrrol-2-Yl)Methyl]Phosphonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to meet the stringent requirements of GMP environments for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed due to sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.