Description

Methyl 2-Bromo-3,3,3-Trifluoropropionate is a versatile fluorinated building block of significant importance in advanced organic synthesis. This compound is valued for its ability to introduce both bromine and trifluoromethyl groups, enabling the construction of complex molecules with tailored properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the CF3 group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Nucleophilic Substitution Scaffold: The bromine moiety is readily displaced by various nucleophiles, facilitating rapid diversification of molecular structures.

Basic Information

Item	Detail
Product Name	Methyl 2-Bromo-3,3,3-Trifluoropropionate
CAS No.	113816-36-7
Molecular Formula	C4H4BrF3O2
Molecular Weight	221.0 g/mol
Synonyms	2-Bromo-3,3,3-trifluoropropionic Acid Methyl Ester; Methyl α-Bromo-β,β,β-trifluoropropionate; Methyl 2-Bromo-3,3,3-trifluoropropanoate; 3,3,3-Trifluoro-2-bromopropionic Acid Methyl Ester; 2-Bromo-3,3,3-trifluoropropanoic Acid Methyl Ester; Bromotrifluoropropionate Methyl Ester; MFCD 22526067
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-3,3,3-Trifluoropropionate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and strong oxidizing agents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.