Description

3-(tert-Butyldimethylsilyloxy)Glutaric Acid is a high-purity, protected glutaric acid derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which offers excellent stability under a wide range of reaction conditions, enabling precise multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), complex natural products, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide & Prostaglandin Synthesis: Used in the preparation of peptide mimetics and prostaglandin analogs due to its protected carboxylic acid functionality.
• Asymmetric Synthesis: Serves as a versatile building block for constructing chiral centers in natural product total synthesis.
• Agrochemical Research: Employed in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Can be utilized to synthesize functionalized polymers and specialty chemicals with specific properties.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and catalysis studies.

Basic Information

Product Name	3-(tert-Butyldimethylsilyloxy)Glutaric Acid
CAS No.	113794-48-2
Molecular Formula	C11H22O5Si
Molecular Weight	262.38 g/mol
Synonyms	3-[(tert-Butyldimethylsilyl)oxy]pentanedioic acid; Glutaric acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 3-(TBDMS-oxy)glutaric acid; 3-(tert-Butyldimethylsiloxy)glutaric acid; 3-Hydroxyglutaric acid TBDMS ether; 3-O-TBDMS-glutaric acid; 3-(tert-Butyl(dimethyl)silyl)oxy)pentanedioic acid; TBDMS-protected 3-hydroxyglutaric acid
EINECS	Contact for details

Quality Control

Our 3-(tert-Butyldimethylsilyloxy)Glutaric Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, ensuring traceability and reliability for our global B2B partners in research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.