Description

Dexmedetomidine is a highly potent and selective α-2 adrenergic receptor agonist. It is a critical active pharmaceutical ingredient (API) valued for its sedative, analgesic, and anxiolytic properties with minimal respiratory depression. This compound is essential for the formulation of injectable sedatives used in intensive care units and surgical settings. Global pharmaceutical manufacturers and research institutions rely on high-purity Dexmedetomidine CAS NO 113775-47-6 for developing safe and effective anesthetic and sedative products.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable sedative formulations for procedural sedation and intensive care.
• Anesthesia Adjunct: Used to reduce requirements for other anesthetic agents during surgery, improving hemodynamic stability.
• Veterinary Medicine: Employed for sedation and analgesia in veterinary surgical and clinical procedures.
• Clinical Research: Serves as a reference standard and key material in pharmacological studies of α-2 adrenergic pathways.
• Premedication: Facilitates anxiolysis and sedation prior to surgical or diagnostic procedures.
• Drug Delivery Development: Used in research for developing novel sustained-release or targeted delivery systems for sedatives.

Basic Information

Product Name	Dexmedetomidine
CAS No.	113775-47-6
Molecular Formula	C13H16N2
Molecular Weight	200.28 g/mol
Synonyms	Dexmedetomidine Hydrochloride (common salt form); (S)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole; MPV-1440; Precedex™ (brand name); Dexdomitor™ (veterinary brand); Dexmedetomidina; Dexmedetomidinum
EINECS	Contact for details

Quality Control

Our Dexmedetomidine is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each batch. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed in a dry environment away from direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Optical Rotation	[α]20/D: Specific range provided on COA
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.