Description

Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy-, Methyl is a specialized organic compound featuring a unique molecular structure that combines amino, hydroxy, and ester functional groups. This compound serves as a versatile chiral building block and protected amino acid derivative, crucial for the synthesis of complex molecules where stereochemical control is paramount. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing peptide mimetics, active pharmaceutical ingredients (APIs), and other high-value bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in peptide and peptidomimetic research.
• Peptide Chemistry: Used as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce stereocenters.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive handles.
• Agrochemical Research: Serves as a building block for the development of advanced, chiral active ingredients with specific biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy-, Methyl
CAS No.	113525-87-4
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	Methyl 3-[(tert-Butoxycarbonyl)amino]-2-hydroxypropanoate; Methyl 2-Hydroxy-3-[(tert-butoxycarbonyl)amino]propanoate; Boc-L-Serine methyl ester; Boc-Ser-OMe; (2S)-3-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-2-hydroxypropanoic acid methyl ester; N-Boc-L-serine methyl ester; L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Hydroxy-, Methyl adheres to stringent quality protocols suitable for GMP and R&D applications. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure consistent chemical and stereochemical integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.