Description

L-Leucine, 4-Methyl-, Methyl Ester CAS NO 113520-44-8 is a specialized amino acid derivative, specifically the methyl ester of 4-methyl-L-leucine. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, prized for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for applications such as peptide synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs) and therapeutic peptides.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide chemistry.
• Agrochemical Research: Serves as a precursor in the synthesis of specialized amino acid-based herbicides, fungicides, or plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of complex organic molecules for flavors, fragrances, and advanced materials.
• Biochemical Research: Utilized in metabolic studies, enzyme substrate development, and as a standard in analytical chromatography.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective catalytic reactions.

Basic Information

Product Name	L-Leucine, 4-Methyl-, Methyl Ester
CAS No.	113520-44-8
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	Methyl (2S)-2-amino-4-methylpentanoate; (S)-2-Amino-4-methylpentanoic acid methyl ester; L-4-Methylleucine methyl ester; Methyl L-4-methylleucinate; 4-Methyl-L-leucine methyl ester; (S)-Methyl 2-amino-4-methylpentanoate; L-tert-Leucine methyl ester (common name variant); Methyl L-tert-leucinate
EINECS	Contact for details

Quality Control

Our L-Leucine, 4-Methyl-, Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.