Description

9-Epi-Artemisinin is a key stereoisomer of the potent antimalarial compound artemisinin, distinguished by its unique epimeric configuration at the C-9 position. This structural variation makes it a critical intermediate and reference standard in pharmaceutical research for the development of novel antimalarial agents and the study of structure-activity relationships. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of artemisinin derivatives and advanced pharmacological studies.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in the production of artemisinin-based drugs.
• Medicinal Chemistry Research: Used as a crucial building block and intermediate in the synthesis of novel artemisinin derivatives with potential enhanced efficacy or reduced resistance.
• Biological Activity Studies: Employed in in-vitro and in-vivo studies to investigate the stereochemical impact on antimalarial, anticancer, or other therapeutic activities.
• Process Development & Optimization: Acts as a model compound for developing and scaling up synthetic routes for complex sesquiterpene lactones.
• Academic & Institutional Research: Essential for universities and research labs focusing on natural product chemistry, drug discovery, and parasitology.

Basic Information

Product Name	9-Epi-Artemisinin
CAS No.	113472-97-2
Molecular Formula	C15H22O5
Molecular Weight	282.33 g/mol
Synonyms	(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one; 9-Epiqinghaosu; Arteannuin B; 9-Epideoxyarteannuin B; (+)-9-Epiartemisinin
EINECS	Contact for details

Quality Control

Our 9-Epi-Artemisinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to ensure the material meets the stringent requirements for pharmaceutical research and reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.