Description

1-[2-(Trimethylsilyl)Ethoxycarbonyloxy]Benzotriazole is a specialized organosilicon-protected benzotriazole derivative, primarily utilized as a versatile reagent in organic synthesis. This compound is valued for its role as a protective group for carboxylic acids and as a coupling agent, offering enhanced stability and selectivity in sensitive reactions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity synthetic building blocks.

Application

• Peptide Synthesis: Employed as a coupling reagent or as a protecting group for carboxylic acids during solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the manufacture of advanced pesticides and herbicides where specific functional group protection is required.
• Organic Synthesis Reagent: Acts as a versatile reagent for the formation of esters and amides under mild conditions.
• Material Science Research: Utilized in the development of novel polymers and functional materials that require silicon-containing precursors.
• Chemical Biology: Applied in the synthesis of probes and modified biomolecules for biochemical and diagnostic applications.

Basic Information

Item	Detail
Product Name	1-[2-(Trimethylsilyl)Ethoxycarbonyloxy]Benzotriazole
CAS No.	113306-55-1
Molecular Formula	C14H21N3O3Si
Molecular Weight	307.42 g/mol
Synonyms	1-[(2-Trimethylsilyl)ethoxycarbonyloxy]benzotriazole; Troc-OSiMe3; 1-[(2-Trimethylsilyl)ethoxycarbonyloxy]-1H-benzotriazole; 1H-Benzotriazole, 1-[(2-(trimethylsilyl)ethoxy)carbonyl]oxy]-; Benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate related reagent; Silicon-protected benzotriazole carbonate; TMSEC-OBt; (2-Trimethylsilyl)ethyl benzotriazol-1-yl carbonate
EINECS	Contact for details

Quality Control

Our 1-[2-(Trimethylsilyl)Ethoxycarbonyloxy]Benzotriazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.