Description

Methyl 3-(Dimethylamino)-2-Isocyanoacrylate is a versatile and highly reactive chemical building block. This compound is valued for its unique isocyano and acrylate functionalities, enabling its use in the synthesis of complex heterocyclic structures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of heterocyclic compounds, including imidazoles and pyrroles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel fungicides, herbicides, and insecticides by providing a reactive handle for constructing complex bioactive molecules.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers and functional materials.
• Chemical Synthesis: Employed in multi-component reactions (MCRs), such as the Ugi and Passerini reactions, to efficiently build molecular complexity in a single step.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways in laboratory settings.

Basic Information

Product Name	Methyl 3-(Dimethylamino)-2-Isocyanoacrylate
CAS No.	113212-14-9
Molecular Formula	C8H12N2O2
Molecular Weight	168.20 g/mol
Synonyms	Methyl 2-Isocyano-3-(dimethylamino)acrylate; 2-Isocyano-3-(dimethylamino)acrylic Acid Methyl Ester; Methyl (Dimethylamino)(isocyano)acetate; Methyl α-Isocyano-β-(dimethylamino)acrylate; 3-(Dimethylamino)-2-isocyanoacrylic Acid Methyl Ester; NSC 405122; Methyl 3-(N,N-Dimethylamino)-2-isocyanoacrylate
EINECS	Contact for details

Quality Control

Our Methyl 3-(Dimethylamino)-2-Isocyanoacrylate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.