Description

5'-Aminospiro[1,3-Dioxolane-2,3'-Indol]-2'(1'H)-One is a specialized spirocyclic indole derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. Its unique fused ring structure containing both an indole and a 1,3-dioxolane moiety makes it a versatile building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting neurological or oncological pathways.
• Organic Synthesis Building Block: Used in the construction of complex spirocyclic and heterocyclic compounds for medicinal chemistry and material science research.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products, leveraging its unique heterocyclic scaffold.
• Academic & Institutional R&D: A valuable reagent for methodological studies in synthetic organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors or specialty polymers with specific electronic properties.

Basic Information

Product Name	5'-Aminospiro[1,3-Dioxolane-2,3'-Indol]-2'(1'H)-One
CAS No.	113207-59-3
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	5'-Amino-1'H-spiro[1,3-dioxolane-2,3'-indole]-2'-one; 2'-Oxo-1'H-spiro[1,3-dioxolane-2,3'-indol]-5'-amine; 5'-Aminospiro[1,3-dioxolane-2,3'-indolin]-2'-one; Spiro[1,3-dioxolane-2,3'-indol]-2'(1'H)-one, 5'-amino-; 113207-59-3; 5-Aminospiro(1,3-dioxolane-2,3'-indol)-2'(1'H)-one; 5'-Amino-spiro[1,3-dioxolane-2,3'-indolin]-2'-one
EINECS	Contact for details

Quality Control

Our 5'-Aminospiro[1,3-Dioxolane-2,3'-Indol]-2'(1'H)-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, meeting the exacting standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.