Description

3'-Chloro-2'-Hydroxy-4-Methoxychalcone is a synthetic chalcone derivative, a key intermediate in organic synthesis and pharmaceutical research. This compound matters for its role as a versatile building block in the development of novel bioactive molecules, particularly in medicinal chemistry. Industries that need it include pharmaceutical R&D, agrochemical development, and academic research institutions focused on synthesizing new chemical entities with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, or microbial infections.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Serves as a starting material for creating new pesticides or herbicides, leveraging its chalcone backbone.
• Chemical Biology Probe: Utilized in biochemical assays to study protein-ligand interactions or enzyme inhibition mechanisms.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create more complex heterocyclic compounds, such as flavones or pyrazolines.
• Material Science Research: Investigated for potential applications in organic electronics or as a component in advanced polymeric materials due to its conjugated system.

Basic Information

Product Name	3'-Chloro-2'-Hydroxy-4-Methoxychalcone
CAS No.	113192-16-8
Molecular Formula	C₁₇H₁₅ClO₃
Molecular Weight	302.75 g/mol
Synonyms	1-(3-Chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; (E)-1-(3-Chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one; 3'-Chloro-2'-hydroxy-4'-methoxychalcone; 2-Propen-1-one, 1-(3-chloro-2-hydroxyphenyl)-3-(4-methoxyphenyl)-, (E)-; Chalcone, 3'-chloro-2'-hydroxy-4-methoxy-; 3'-Chloro-2'-hydroxy-4-methoxychalkone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-2'-Hydroxy-4-Methoxychalcone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.