Description

1H-Indole-2-Carboxylic Acid, 4-Fluoro-, Methyl Ester is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its specific molecular architecture enables targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced efficacy and environmental stability.
• Fine Chemical Manufacturing: Serves as a versatile building block for synthesizing complex fluorinated organic compounds used in material science and specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocyclic chemistry.
• Biochemical Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid, 4-Fluoro-, Methyl Ester
CAS No.	113162-36-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	4-Fluoro-1H-indole-2-carboxylic acid methyl ester; Methyl 4-fluoro-1H-indole-2-carboxylate; 4-Fluoroindole-2-carboxylic acid methyl ester; 1H-Indole-2-carboxylic acid, 4-fluoro-, methyl ester; 4-Fluoro-2-(methoxycarbonyl)indole; Methyl 4-fluoroindole-2-carboxylate; 4-Fluoro-2-indolecarboxylic acid methyl ester; 113162-36-0
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid, 4-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.