Description

1-Pyrrolidinecarboxylic Acid, 2-Formyl-, Methyl Ester, (2S)- (9Ci) is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its unique structure, which incorporates both a formyl group and a pyrrolidine carboxylic acid ester moiety, making it a versatile precursor for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring specific stereochemistry. CAS No. 113089-16-0.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereoisomers are required for optimal activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the development of novel chiral ligands and organocatalysts.
• Peptidomimetics Research: Employed in medicinal chemistry for constructing proline analogs and other constrained peptide-like structures to modulate biological activity.
• Fine Chemical Production: Acts as a versatile building block for custom synthesis and the manufacture of specialty chemicals with high added value.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxylic Acid, 2-Formyl-, Methyl Ester, (2S)- (9Ci)
CAS No.	113089-16-0
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(S)-2-Formylpyrrolidine-1-carboxylic acid methyl ester; Methyl (S)-2-formylpyrrolidine-1-carboxylate; L-Proline, 2-formyl-, methyl ester; (2S)-2-Formyl-1-pyrrolidinecarboxylic acid methyl ester; 1-Pyrrolidinecarboxylic acid, 2-formyl-, methyl ester, (S)-; (S)-1-(Methoxycarbonyl)-2-formylpyrrolidine; (S)-Methyl 2-formylpyrrolidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-Pyrrolidinecarboxylic Acid, 2-Formyl-, Methyl Ester, (2S)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, identity confirmation by IR and NMR, and precise assay determination. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.