Description

Boc-D-Aspartic Acid 4-Cyclohexyl Ester is a high-purity, non-natural amino acid derivative extensively used in advanced organic synthesis. This compound is a critical chiral building block for the construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of peptides containing D-aspartic acid residues.
• Pharmaceutical Research: Serves as a crucial building block in the discovery and development of protease inhibitors, receptor agonists/antagonists, and other therapeutic peptides.
• Medicinal Chemistry: Used to introduce the D-aspartic acid moiety with a protected side chain into novel chemical entities to study structure-activity relationships (SAR).
• Bioconjugation: Can be employed in the synthesis of peptide-based linkers or tags for bioconjugation applications in drug delivery systems.
• Chemical Biology Probes: Useful for creating labeled or modified peptide probes to study biological processes and enzyme functions.

Basic Information

Product Name	Boc-D-Aspartic Acid 4-Cyclohexyl Ester
CAS No.	112898-18-7
Molecular Formula	C₁₅H₂₅NO₆
Molecular Weight	315.36 g/mol
Synonyms	Boc-D-Asp(OcHex)-OH; (R)-2-((tert-Butoxycarbonyl)amino)succinic acid 4-cyclohexyl ester; tert-Butyl (R)-(4-(cyclohexyloxy)-3-carboxy-4-oxobutyl)carbamate; Boc-D-Asp(OcHex)-OH; N-(tert-Butoxycarbonyl)-D-aspartic acid 4-cyclohexyl ester; Boc-D-Asp(Ocyclohexyl)-OH; D-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-cyclohexyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Aspartic Acid 4-Cyclohexyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.