Description

n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-Glycine Ethyl Ester is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients and catalysts.

Application

• As a chiral auxiliary or ligand in asymmetric catalytic reactions.
• Key intermediate in the synthesis of enantiomerically pure pharmaceutical actives, particularly in central nervous system (CNS) and cardiovascular drug research.
• Building block for novel peptide mimetics and enzyme inhibitors.
• Precursor for advanced chiral catalysts used in industrial-scale chemical manufacturing.
• Starting material for the development of specialty chemicals and high-value fine chemicals.
• Use in academic and industrial R&D for method development in stereoselective synthesis.

Basic Information

Product Name	n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-Glycine Ethyl Ester
CAS No.	112835-62-8
Molecular Formula	C18H21NO3
Molecular Weight	299.37 g/mol
Synonyms	(1R,2S)-2-Hydroxy-1,2-diphenylethylglycine ethyl ester; (R,S)-Phenylglycinol-derived glycine ethyl ester; Ethyl (2S)-2-[[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino]acetate; Glycine, N-[(1R,2S)-2-hydroxy-1,2-diphenylethyl]-, ethyl ester; Chiral glycine ethyl ester derivative; (1R,2S)-1,2-Diphenyl-2-hydroxyethylaminoacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our n-[(1R,2S)-2-Hydroxy-1,2-Diphenylethyl]-Glycine Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.