Description

(S)-Benzyl 2-Oxooxazolidine-5-Carboxylate is a high-value chiral building block and synthetic intermediate of significant importance in modern pharmaceutical chemistry. Its core value lies in its stereochemically defined oxazolidinone structure, which is a privileged scaffold for constructing bioactive molecules with precise three-dimensional orientation. This compound is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel antibiotics, enzyme inhibitors, and other chiral active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those containing the oxazolidinone pharmacophore.
• Antibiotic Research: Serves as a crucial precursor in the development of novel oxazolidinone-class antibiotics, such as linezolid analogs.
• Asymmetric Synthesis: Used as a chiral auxiliary or starting material in stereoselective reactions to introduce defined stereocenters into target molecules.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the construction of focused libraries for high-throughput screening.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for advanced pharmaceutical intermediates.
• Academic & Institutional Research: A valuable reagent for investigating new synthetic methodologies and catalytic processes in organic chemistry laboratories.

Basic Information

Product Name	(S)-Benzyl 2-Oxooxazolidine-5-Carboxylate
CAS No.	112663-80-6
Molecular Formula	C11H11NO4
Molecular Weight	221.21 g/mol
Synonyms	(5S)-5-(Benzyloxycarbonyl)-1,3-oxazolidin-2-one; (S)-5-(Benzyloxycarbonyl)oxazolidin-2-one; (S)-Benzyl 5-oxo-1,3-oxazolidine-5-carboxylate; (S)-N-Carbobenzyloxy-2-amino-1,3-propanediol cyclic carbonate; (S)-2-Oxo-3-oxazolidinecarboxylic acid benzyl ester; (S)-Cbz-Aminodiol Cyclic Carbonate; (S)-5-Carbobenzyloxy-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Oxooxazolidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the exacting standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.