Description

Methyl (2R)-2-Hydroxy-4-Methylpentanoate is a high-purity chiral ester, a key building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for producing enantiomerically pure compounds. This product is critical for research and development in the pharmaceutical and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring specific stereocenters.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to construct complex molecules.
• Flavor and Fragrance Precursor: Serves as a building block for the synthesis of specific, high-value aroma compounds.
• Agrochemical Research: Employed in the development of chiral active ingredients for crop protection products.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands for metal-catalyzed transformations.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and total synthesis projects.

Basic Information

Product Name	Methyl (2R)-2-Hydroxy-4-Methylpentanoate
CAS No.	112529-90-5
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(R)-Methyl 2-Hydroxy-4-methylvalerate; (R)-Methyl 2-Hydroxy-4-methylpentanoate; (2R)-2-Hydroxy-4-methylpentanoic Acid Methyl Ester; Methyl (R)-2-Hydroxy-4-methylvalerate; L-Leucine Methyl Ester Derivative; (R)-2-Hydroxyisocaproic Acid Methyl Ester; Methyl (R)-2-Hydroxy-4-methylpentanoate
EINECS	Contact for details

Quality Control

Our Methyl (2R)-2-Hydroxy-4-Methylpentanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.