Description

Methyl(2E,4S)-(-)-4-(Phenylmethoxy)Pent-2-Enoate CAS NO 112489-57-3 is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable precursor for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), especially those requiring specific stereocenters.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions, including asymmetric hydrogenation, cycloaddition, and cross-coupling reactions.
• Natural Product Synthesis: Serves as a precursor in the total synthesis of natural products and bioactive compounds with defined (2E,4S) configuration.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials where precise molecular architecture is required.
• Catalyst and Ligand Development: Used in the research and development of novel chiral catalysts and ligands for catalytic processes.
• Academic and R&D Laboratories: A critical reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Item	Details
Product Name	Methyl(2E,4S)-(-)-4-(Phenylmethoxy)Pent-2-Enoate
CAS No.	112489-57-3
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	(2E,4S)-Methyl 4-(Benzyloxy)-2-pentenoate; Methyl (2E,4S)-4-(Benzyloxy)pent-2-enoate; (-)-Methyl (2E,4S)-4-(Phenylmethoxy)-2-pentenoate; (4S)-Methyl 4-(Benzyloxy)-2-pentenoate; (2E,4S)-4-(Benzyloxy)-2-pentenoic Acid Methyl Ester; (S,E)-Methyl 4-(Benzyloxy)pent-2-enoate; Chiral Benzyloxy Pentenoate Ester
EINECS	Contact for details

Quality Control

Our production of Methyl(2E,4S)-(-)-4-(Phenylmethoxy)Pent-2-Enoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC/MS, to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.