Description

5-Isoxazolidinecarboxylicacid,4-Amino-3-Oxo-,Methylester,trans-(9Ci) is a specialized heterocyclic building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those containing the isoxazolidine scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Reagent: Serves as a versatile synthon in academic and industrial laboratories for constructing complex nitrogen- and oxygen-containing heterocycles.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Chemical Biology Probe Development: Utilized as a precursor for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	5-Isoxazolidinecarboxylicacid,4-Amino-3-Oxo-,Methylester,trans-(9Ci)
CAS No.	112458-08-9
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	trans-4-Amino-3-oxo-5-isoxazolidinecarboxylic acid methyl ester; Methyl (4-amino-3-oxo-2-isoxazolidine)carboxylate; 4-Amino-3-oxoisoxazolidine-5-carboxylic acid methyl ester; 5-Isoxazolidinecarboxylic acid, 4-amino-3-oxo-, methyl ester, trans-; 112458-08-9; trans-Methyl 4-amino-3-oxoisoxazolidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports the stringent requirements of pharmaceutical and fine chemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.