Description

1H-Pyrazole-1-Carbonylisocyanate(9Ci) is a specialized organic building block belonging to the pyrazole-carbonyl isocyanate class of compounds. This high-purity intermediate is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research and development. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrazole moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for synthesizing specialized polymers and functional materials with tailored properties.
• Chemical Biology Probe Development: Employed in the creation of isocyanate-based probes for studying enzyme activity and protein labeling.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical market.

Basic Information

Item	Detail
Product Name	1H-Pyrazole-1-Carbonylisocyanate(9Ci)
CAS No.	112423-48-0
Molecular Formula	C5H3N3O2
Molecular Weight	137.10 g/mol
Synonyms	1H-Pyrazole-1-carbonyl isocyanate; Pyrazole-1-carbonyl isocyanate; 1-Pyrazolecarbonyl isocyanate; Isocyanic acid 1H-pyrazole-1-carbonyl ester; 1-Carbamoylpyrazole isocyanate; (1H-Pyrazol-1-yl)carbonyl isocyanate; 112423-48-0; 1-Pyrazolylcarbonyl isocyanate
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Carbonylisocyanate(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.