Description

Butanedioic Acid, 2-(2-Methylpropyl)-, 4-(1,1-Dimethylethyl) Ester, (2R)- is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. Its defined stereochemistry and unique esterified succinic acid structure make it a valuable intermediate for constructing complex molecules with specific spatial orientations. This compound is primarily sought after by research institutions and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty performance materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly where stereochemical purity is critical for biological activity.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Flavor and Fragrance Industry: Potential use in creating stereospecific aroma chemicals and flavor compounds.
• Material Science Research: Employed in the development of chiral polymers and liquid crystals with specialized optical properties.
• Academic and R&D Laboratories: A valuable reference standard and building block for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Butanedioic Acid, 2-(2-Methylpropyl)-, 4-(1,1-Dimethylethyl) Ester, (2R)-
CAS No.	112245-04-2
Molecular Formula	C13H24O4
Molecular Weight	244.33 g/mol
Synonyms	(2R)-2-Isobutylsuccinic Acid 4-tert-Butyl Ester; (R)-2-Isobutylsuccinic Acid 1-tert-Butyl Ester; (R)-4-tert-Butyl 2-Isobutyl Succinate; (R)-mono-tert-Butyl 2-Isobutylsuccinate; (2R)-2-(2-Methylpropyl)butanedioic acid 4-(1,1-dimethylethyl) ester; (R)-H-Ser(tBu)-OtBu (protected derivative precursor); Chiral Isobutyl Succinate tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of Butanedioic Acid, 2-(2-Methylpropyl)-, 4-(1,1-Dimethylethyl) Ester, (2R)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. The material is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profile is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.