Description

5-Isoxazolidinecarboxylicacid,4-Amino-3-Oxo-,Methylester,(4S-Cis)-(9Ci) is a high-purity, stereochemically defined heterocyclic building block. This compound is valued for its role as a key chiral intermediate in the synthesis of complex bioactive molecules, offering precise control over the final product's stereochemistry. It is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutics, including enzyme inhibitors and other pharmacologically active agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Enzyme Inhibitor Synthesis: Serves as a core structural component in the design and synthesis of potent enzyme inhibitors for therapeutic applications.
• Organic Synthesis Building Block: Used in advanced organic synthesis to construct complex heterocyclic frameworks found in natural products and specialty chemicals.
• Biochemical Research: Employed in biochemical studies as a precursor or standard for investigating biological pathways and mechanisms.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.

Basic Information

Product Name	5-Isoxazolidinecarboxylicacid,4-Amino-3-Oxo-,Methylester,(4S-Cis)-(9Ci)
CAS No.	112244-07-2
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	(4S-cis)-4-Amino-3-oxo-5-isoxazolidinecarboxylic acid methyl ester; Methyl (4S,5R)-4-amino-3-oxo-1,2-oxazolidine-5-carboxylate; 4-Amino-3-oxo-5-isoxazolidinecarboxylic acid methyl ester, (4S-cis)-; 112244-07-2; (4S,5R)-4-Amino-3-oxo-isoxazolidine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.