Description

7-Bromo-1,2,3,4-Tetrahydronaphthalene-1-Spiro-2'-(1',3'-Dioxacyclopentane) is a high-value, multifunctional spirocyclic organic intermediate with a unique fused-ring structure. This compound is critical for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules in pharmaceutical and materials science research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and the synthesis of novel functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its bromine atom for further functionalization.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced organic electronic materials due to its rigid, conjugated backbone.
• Chemical Biology Probes: Utilized as a core structure for designing molecular probes and tags to study biological processes and protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and cross-coupling reactions.

Basic Information

Product Name	7-Bromo-1,2,3,4-Tetrahydronaphthalene-1-Spiro-2'-(1',3'-Dioxacyclopentane)
CAS No.	111773-13-8
Molecular Formula	C₁₃H₁₅BrO₂
Molecular Weight	283.16 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydronaphthalen-1-spiro-2'-(1',3'-dioxolane); 7-Bromo-1,2,3,4-tetrahydronaphthalene-1-spiro-2'-(1',3'-dioxolane); 7-Bromotetralin-1-spiro-2'-(1',3'-dioxolane); 1-(7-Bromo-1,2,3,4-tetrahydronaphthalen-1-yl)-1,3-dioxolane; 7-Bromo-1,2,3,4-tetrahydrospiro[naphthalene-1,2'-[1,3]dioxolane]; Spiro[1,3-dioxolane-2,1'-(7'-bromo-1',2',3',4'-tetrahydronaphthalene)]; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 7-Bromo-1,2,3,4-Tetrahydronaphthalene-1-Spiro-2'-(1',3'-Dioxacyclopentane) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.