Description

Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1S,4R)- (9Ci) is a high-purity, chiral bicyclic diene derivative with significant utility in advanced organic synthesis. Its rigid, strained structure and defined stereochemistry make it a valuable building block for complex molecular architectures, particularly in pharmaceutical and specialty chemical research. This compound is essential for chemists developing novel active pharmaceutical ingredients (APIs), agrochemicals, and performance materials requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, especially those with bridged ring systems.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands for transition metal catalysis.
• Diels-Alder Reaction Diene Component: Exploits its reactive diene moiety in cycloaddition reactions to construct polycyclic frameworks.
• Agrochemical Research: Serves as an intermediate in creating novel pesticides and herbicides with specific stereoisomeric activity.
• Material Science: A precursor for specialty polymers and advanced organic materials with unique thermal or optical properties.
• Academic & R&D: A valuable tool for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1S,4R)- (9Ci)
CAS No.	111613-51-5
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	(1S,4R)-Bicyclo[2.2.1]hepta-2,5-diene-2-carboxylic acid methyl ester; (1S,4R)-2,5-Norbornadiene-2-carboxylic acid methyl ester; Methyl (1S,4R)-bicyclo[2.2.1]hepta-2,5-diene-2-carboxylate; (1S,4R)-exo-2,3-Didehydronorbornane-2-carboxylic acid methyl ester; (1S,4R)-Methyl 2,5-norbornadiene-2-carboxylate; Chiral norbornadiene ester; (1S,4R)-NBD-COOMe
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hepta-2,5-Diene-2-Carboxylic Acid, Methyl Ester, (1S,4R)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.