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n-(4-Azidosalicyl)Galactosamine CAS NO 111583-52-9


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CAS No.:111583-52-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(4-Azidosalicyl)Galactosamine is a specialized biochemical reagent featuring a photoreactive azido group and a galactosamine moiety. This compound is engineered for applications in photoaffinity labeling and bioconjugation, enabling the covalent cross-linking of biomolecules upon exposure to UV light. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, proteomics, and pharmaceutical development for studying carbohydrate-protein interactions and developing targeted drug delivery systems.

Application

  • Photoaffinity Labeling Probe: Used to identify and characterize carbohydrate-binding proteins (lectins) and enzymes in complex biological systems.
  • Bioconjugation and Linker Chemistry: Serves as a key intermediate for synthesizing glycan arrays, diagnostic probes, and antibody-drug conjugates (ADCs).
  • Glycobiology Research: Essential for studying galactose-mediated cell signaling, recognition events, and metabolic pathways.
  • Proteomic Analysis: Facilitates the capture and isolation of glycoproteins for mass spectrometry and functional studies.
  • Drug Discovery: Employed in the development of targeted therapeutics that exploit specific sugar-recognition mechanisms.
  • Surface Functionalization: Used to modify biosensor surfaces, microarrays, and nanoparticles with bioactive galactose motifs.

Basic Information

Product Name n-(4-Azidosalicyl)Galactosamine
CAS No. 111583-52-9
Molecular Formula C₁₃H₁₆N₄O₆
Molecular Weight 324.29 g/mol
Synonyms 4-Azidosalicyl Galactosamine; N-(4-Azido-2-hydroxybenzoyl)galactosamine; Galactosamine, N-(4-azidosalicyl)-; 4-Azido-2-hydroxy-N-(2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)benzamide; Azidosalicyl Galactosamine; Photoactivatable Galactosamine Derivative; ASG; N-4-Azidosalicylgalactosamine
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Quality Control

Our n-(4-Azidosalicyl)Galactosamine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous requirements of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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