Description

(Bromoethynyl)Triisopropylsilane CAS NO 111409-79-1 is a highly versatile organosilicon reagent featuring a reactive bromoethynyl group protected by a robust triisopropylsilyl (TIPS) moiety. This compound is critical for advanced organic synthesis, enabling efficient carbon-carbon bond formation and serving as a key building block for complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing acetylenic scaffolds and functionalized intermediates.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for Sonogashira and other cross-coupling reactions to introduce acetylene functionalities into active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific acetylene-based structures.
• Materials Science & Polymer Chemistry: Serves as a monomer or functionalization agent for creating conductive polymers, advanced coatings, and specialty materials with tailored properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts used in asymmetric synthesis and homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized to create labeled probes and bioconjugates for imaging, diagnostics, and target identification studies.
• Academic & Industrial R&D: A fundamental reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	(Bromoethynyl)Triisopropylsilane
CAS No.	111409-79-1
Molecular Formula	C11H21BrSi
Molecular Weight	261.27 g/mol
Synonyms	1-Bromo-2-(triisopropylsilyl)ethyne; Bromo[(triisopropylsilyl)ethynyl]; TIPS-Bromoacetylene; Triisopropyl((bromoethynyl))silane; (Bromoethynyl)triisopropylsilane; Bromo(triisopropylsilyl)acetylene; (Triisopropylsilyl)bromoacetylene; 1-Bromo-2-(triisopropylsilyl)acetylene
EINECS	Contact for details

Quality Control

Our (Bromoethynyl)Triisopropylsilane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is characterized by comprehensive analytical techniques including NMR, GC, and HPLC to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.