Description

(-)-Bis[(S)-1-(Ethoxycarbonyl)Ethyl] Fumarate is a high-purity, chiral diester derivative of fumaric acid, valued for its role as a key synthetic intermediate in the production of optically active compounds. Its defined stereochemistry is critical for applications requiring precise molecular configuration, such as in advanced pharmaceutical synthesis. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce chiral complexity into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for drugs targeting specific biological pathways.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective reactions to construct complex molecules with high enantiomeric purity.
• Agrochemical Research: Serves as an intermediate in developing enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: A precursor for synthesizing chiral ligands used in asymmetric catalysis, such as hydrogenation or cross-coupling reactions.
• Polymer Modification: Can be incorporated into polymer backbones to impart chirality or specific functional groups for advanced material science applications.
• Academic and R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes involving fumarate esters.

Basic Information

Product Name	(-)-Bis[(S)-1-(Ethoxycarbonyl)Ethyl] Fumarate
CAS No.	111293-23-3
Molecular Formula	C14H20O8
Molecular Weight	316.30 g/mol
Synonyms	(S,S)-Diethyl 2,2'-(E)-ethene-1,2-diylbis(2-methyl-3-oxopropanoate); (S,S)-Diethyl 2,2'-(fumaroylbis(2-methyl-3-oxopropanoate); (-)-Diethyl (S,S)-2,2'-(1,2-Ethenediyl)bis[2-methyl-3-oxopropanoate]; Fumaric Acid Bis[(S)-1-(Ethoxycarbonyl)Ethyl] Ester; (S)-1-(Ethoxycarbonyl)Ethyl Fumarate Dimer; Chiral Diethyl Fumarate Derivative
EINECS	Contact for details

Quality Control

Our (-)-Bis[(S)-1-(Ethoxycarbonyl)Ethyl] Fumarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.