Description

2-Isocyanato-4,6-dimethoxypyrimidine is a specialized heterocyclic isocyanate building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of high-value, performance-driven molecules, enabling the formation of stable urea linkages under mild conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Polymer Modification: Serves as a reactive monomer for introducing pyrimidine functionality into polyurethanes and other polymers to tailor thermal and mechanical properties.
• Cross-linking Agent: Employed in the formulation of specialty coatings, adhesives, and sealants to improve durability and chemical resistance.
• Bioconjugation Chemistry: Facilitates the stable attachment of small molecules, dyes, or drugs to proteins, antibodies, or nanoparticles for diagnostic and therapeutic applications.
• Material Science Research: Enables the creation of novel organic frameworks (MOFs/COFs) and functional surfaces with specific binding sites.

Basic Information

Product Name	2-Isocyanato-4,6-dimethoxypyrimidine
CAS No.	111284-03-8
Molecular Formula	C7H7N3O3
Molecular Weight	181.15 g/mol
Synonyms	4,6-Dimethoxy-2-pyrimidinyl isocyanate; 2-Isocyanato-4,6-dimethoxy-pyrimidine; 4,6-Dimethoxy-2-isocyanatopyrimidine; 2-Pyrimidinyl isocyanate, 4,6-dimethoxy-; 4,6-Dimethoxypyrimidin-2-yl isocyanate; Isocyanic acid, 4,6-dimethoxy-2-pyrimidinyl ester
EINECS	Contact for details

Quality Control

Our 2-Isocyanato-4,6-dimethoxypyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.