Description

(S)-2-Methyl-Butanedioic Acid-1-Methyl Ester is a high-purity chiral building block of significant value in asymmetric synthesis. This compound matters because its defined stereochemistry enables the precise construction of complex molecules, which is critical for developing pharmaceuticals and fine chemicals with specific biological activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as chiral ligand synthesis and the production of active pharmaceutical ingredients (APIs).

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Used in the synthesis of chiral ligands and catalysts for stereoselective chemical reactions.
• Agrochemical Development: Serves as a precursor for creating enantiomerically specific herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Flavor/Fragrance Synthesis: Employed in the production of high-value specialty chemicals and chiral aroma compounds.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization studies.

Basic Information

Product Name	(S)-2-Methyl-Butanedioic Acid-1-Methyl Ester
CAS No.	111266-16-1
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	(S)-2-Methylsuccinic Acid 1-Methyl Ester; (S)-1-Methoxy-1-oxobutan-2-yl]acetic Acid; Methyl (S)-2-Methylsuccinate; (S)-Methyl 2-Methylsuccinate; (2S)-2-Methylbutanedioic Acid 1-Methyl Ester; (S)-(-)-Methyl 2-Methylsuccinate
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-Butanedioic Acid-1-Methyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.