Description

Propanedioic Acid, 2-(3-Oxocyclopentyl)-, 1,3-Dimethyl Ester is a specialized diester derivative of propanedioic acid (malonic acid) featuring a cyclopentanone moiety, serving as a high-value synthetic intermediate in advanced organic synthesis. Its unique bifunctional structure, combining an active methylene group with a ketone, makes it a versatile building block for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing fused or spiro-cyclic systems, due to its reactive carbonyl and ester functionalities.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its structure can be incorporated to modulate biological activity and selectivity.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialty chemicals, flavors, and fragrances requiring specific cyclic ketone derivatives.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymers with tailored thermal and mechanical properties.
• Academic & R&D Laboratories: Serves as a valuable reagent for methodological development in organic chemistry, including studies on Michael additions, Knoevenagel condensations, and ring-forming reactions.

Basic Information

Product Name	Propanedioic Acid, 2-(3-Oxocyclopentyl)-, 1,3-Dimethyl Ester
CAS No.	111209-96-2
Molecular Formula	C₁₁H₁₆O₅
Molecular Weight	228.24 g/mol
Synonyms	Dimethyl 2-(3-oxocyclopentyl)malonate; 2-(3-Oxocyclopentyl)malonic Acid Dimethyl Ester; Malonic Acid, (3-Oxocyclopentyl)-, Dimethyl Ester; 1,3-Dimethyl 2-(3-oxocyclopentyl)propanedioate; (3-Oxocyclopentyl)malonic Acid Dimethyl Ester; Dimethyl (3-oxocyclopentyl)malonate
EINECS	Contact for details

Quality Control

Our Propanedioic Acid, 2-(3-Oxocyclophenyl)-, 1,3-Dimethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.