Description

1-Piperidinecarboxylic Acid, 2-Hydroxy-, Ethyl Ester CAS NO 111054-63-8 is a specialized piperidine derivative that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its value lies in the combination of a protected amino acid-like structure and a reactive ester group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutics.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Preparation: Precursor for synthesizing novel chiral ligands used in asymmetric catalysis.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs to improve metabolic stability and bioavailability.
• Chemical Biology Probes: Intermediate for creating labeled compounds and molecular probes for biochemical studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers for bespoke molecule production.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 2-Hydroxy-, Ethyl Ester
CAS No.	111054-63-8
Molecular Formula	C8H15NO3
Molecular Weight	173.21 g/mol
Synonyms	Ethyl 2-Hydroxypiperidine-1-carboxylate; 2-Hydroxy-1-piperidinecarboxylic Acid Ethyl Ester; 1-Carbethoxy-2-hydroxypiperidine; 1-(Ethoxycarbonyl)-2-piperidinol; 2-Hydroxypiperidine-1-carboxylic Acid Ethyl Ester; NSC 339586; Ethyl 1-Piperidinecarboxylate, 2-hydroxy- derivative
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid, 2-Hydroxy-, Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure consistency and meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.