Description

1(2H)-Pyridinecarboxylic Acid, 3,4-Dihydro-2-Hydroxy-, Ethyl Ester is a specialized heterocyclic ester derivative of dihydropyridine. This compound serves as a versatile and high-purity chemical intermediate for advanced organic synthesis. It is primarily required by pharmaceutical, agrochemical, and fine chemical research and development teams for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for cardiovascular and neurological targets.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific heterocyclic frameworks.
• Ligand and Catalyst Development: Employed in academic and industrial research to create novel ligands for metal-catalyzed reactions.
• Chemical Research: A valuable reagent for methodological studies in organic chemistry, including cyclization and functionalization reactions.

Basic Information

Product Name	1(2H)-Pyridinecarboxylic Acid, 3,4-Dihydro-2-Hydroxy-, Ethyl Ester
CAS No.	111054-55-8
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	Ethyl 2-hydroxy-3,4-dihydro-1(2H)-pyridinecarboxylate; 2-Hydroxy-3,4-dihydro-1(2H)-pyridinecarboxylic acid ethyl ester; 1,2-Dihydropyridine-2-carboxylic acid, 2-hydroxy-, ethyl ester; Ethyl 2-hydroxypiperidine-2-carboxylate (tautomeric form); DHP Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Pyridinecarboxylic Acid, 3,4-Dihydro-2-Hydroxy-, Ethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. All materials are fully characterized and tested against established internal specifications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.