Description

3-Fluoro-Benzoic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is a high-purity, reactive chemical intermediate belonging to the class of N-hydroxysuccinimide (NHS) esters. This compound is specifically engineered for efficient amide bond formation, serving as a critical building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating amide-linked drug candidates and prodrugs.
• Peptide Synthesis & Bioconjugation: Used for the selective labeling and cross-linking of biomolecules, including proteins, peptides, and antibodies, in biochemical research and diagnostic assay development.
• Agrochemical Research: Employed in the design and synthesis of novel herbicides, fungicides, and plant growth regulators that require the 3-fluorobenzoic acid moiety.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialized polymers and functional materials with tailored properties.
• Chemical Biology Probes: Facilitates the creation of activity-based probes and affinity tags for studying enzyme function and protein interactions.

Basic Information

Product Name	3-Fluoro-Benzoic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester
CAS No.	110920-19-9
Molecular Formula	C11H8FNO4
Molecular Weight	237.19 g/mol
Synonyms	3-Fluorobenzoic Acid N-Hydroxysuccinimide Ester; 3-Fluoro-NHS Benzoate; 3-Fluorobenzoyloxy-2,5-pyrrolidinedione; N-(3-Fluorobenzoyloxy)succinimide; 3-Fluorobenzoic Acid Succinimidyl Ester; 3-FBA-OSu; 3-Fluorobenzoyl NHS Ester; 1-[(3-Fluorobenzoyl)oxy]-2,5-pyrrolidinedione
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Benzoic Acid 2,5-Dioxo-Pyrrolidin-1-Yl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.