Description

Ethyl Tetrahydro-2H-Pyran-2-Carboxylate is a versatile ester derivative of tetrahydro-2H-pyran-2-carboxylic acid, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its significance lies in its ability to introduce functionalized tetrahydropyran motifs, which are core structural elements in numerous bioactive molecules and complex natural products. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing tetrahydropyran or sugar-like scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific stereochemistry.
• Fine Chemical Production: Employed as a precursor for flavors, fragrances, and other specialty chemicals where the tetrahydropyran ring contributes to the desired olfactory or taste profile.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and for constructing complex molecular architectures in medicinal chemistry programs.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Ethyl Tetrahydro-2H-Pyran-2-Carboxylate
CAS No.	110811-34-2
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	Ethyl Tetrahydro-2H-pyran-2-carboxylate; Ethyl Oxane-2-carboxylate; 2-Carbethoxy Tetrahydropyran; Tetrahydro-2H-pyran-2-carboxylic Acid Ethyl Ester; Ethyl 2-Oxane carboxylate; Ethyl Tetrahydropyran-2-carboxylate; 2-Ethoxycarbonyl Tetrahydropyran; Ethyl 2-Tetrahydropyran carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl Tetrahydro-2H-Pyran-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve optimal quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.440 - 1.450
Specific Gravity (20°C)	1.050 - 1.090

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.